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TRETINOIN
Tretinoin is a slightly altered version of vitamin A. Topical tretinoin is available in cream, gel, and liquid forms to treat acne, other skin conditions, and some forms of skin cancer. Tretinoin is also available in oral capsules used to induce remission in people with acute promyelocytic leukemia.
Safetychecker Summary
for Tretinoin
(for details about the summarized interactions, read the full article)
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results. |
Vitamin A* |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
Interactions with Dietary Supplements
Vitamin
A
Large amounts of vitamin A can cause side effects, and oral tretinoin can cause similar side
effects. Combining vitamin A with oral tretinoin is likely to increase the risk of side
effects. People taking oral tretinoin should probably not take more than 10,000 IU of
supplemental vitamin A per day.
Interactions with Foods and Other Compounds
Food
Food enhances absorption of retinoid drugs.1 Tretinoin capsules (Vesanoid®)
should be taken with food.
References:
1. Threlkeld DS, ed. Antineoplastics, Miscellaneous Antineoplastics, Tretinoin. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jul 1996, 685w–5z.
Copyright © 2002 Healthnotes, Inc. All rights reserved. www.healthnotes.com
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article.
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Learn more about the authors of Safetychecker.
The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.
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