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RALOXIFENE

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Raloxifene is a type of drug called a selective estrogen receptor modulator (SERM). It is used to prevent osteoporosis in women after menopause.

Safetychecker Summary for Raloxifene
(for details about the summarized interactions, read the full article)

May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them.	Phytoestrogens
Side effect reduction/prevention	None known
Supportive interaction	None known
Reduced drug absorption/bioavailability	None known
Adverse interaction	None known

Interactions with Herbs

Formononetin
Some chemicals called phytoestrogens, found naturally in plants, have estrogen-like activity; and some people use these phytoestrogens from dietary sources or from supplements to prevent or treat hormone-related health problems. In test tube studies, the estrogenic activity of one phytoestrogen, formononetin, was blocked by raloxifene.¹ Further research is necessary to determine the overall effect of raloxifene on formononetin and other phytoestrogens in humans.

References:

1. Ruh MF, Taylor JA, Howlett AC, Welshons WV. Failure of cannabinoid compounds to stimulate estrogen receptors. Biochem Pharmacol 1997;53:35–41.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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