Combination drugs: Advanced Formula Di-Gel® Tablets, Calcium Rich Rolaids®, Co-Magaldrox, Maalox Plus®, Maalox®, Mucaine®, Mylanta®, Tempo® Tablets
Magnesium hydroxide is used as an antacid for short-term relief of stomach upset and as a laxative for short-term treatment of constipation. Magnesium hydroxide is available in nonprescription products alone and in combination with other nonprescription ingredients to relieve stomach upset.
Safetychecker Summary
for Magnesium Hydroxide
(for details about the summarized interactions, read the full article)
|
Folic Acid Iron* |
|
|
Potassium |
|
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
Interactions with Dietary Supplements
Folic
acid
Folic acid is needed by the body to utilize
vitamin B12. Antacids, including magnesium hydroxide, inhibit folic acid
absorption.1 People taking antacids are advised to supplement with folic acid.
Iron
Antacids, including magnesium hydroxide, may
reduce the absorption of dietary iron. Iron supplements do not require stomach acid for
absorption and one human study found that a magnesium hydroxide/aluminum hydroxide antacid did not decrease
supplemental iron absorption.2
Potassium
Individuals taking potassium-depleting
diuretics and those who are otherwise at risk of developing potassium deficiency (such as
people with chronic diarrhea or vomiting) may
experience a fall in serum potassium levels if they take magnesium without taking additional
potassium.3 This could lead to muscle cramps or, in individuals taking digoxin or digitalis, more serious problems such as cardiac arrhythmias. Individuals who have a
history of potassium deficiency and those who are at risk of developing potassium deficiency,
as well as people taking digoxin or digitalis, should consult a physician before taking
magnesium-containing products.
1. Russell RM, Golner BB, Krasinski SD, et al. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. J Lab Clin Med 1988;112:458–63.
2. O’Neil-Cutting MA, Crosby WH. The effect of antacids on the absorption of simultaneously ingested iron. JAMA 1986;255:1468–70.
3. Dyckner T, Wester PO. Ventricular extrasystoles and intracellular electrolytes before and after potassium and magnesium infusions in patients on diuretic treatment. Am Heart J 1979;97:12–8.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.