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MIRTAZAPINE
Mirtazapine is used to treat people with mental depression, especially those who are also nervous and have trouble sleeping. It is in a class of drugs called tetracyclic antidepressants.
Safetychecker Summary
for Mirtazapine
(for details about the summarized interactions, read the full article)
Check: Other—Before taking any of these supplements or eating any of
these foods with your medication, read this article in full for details. |
Melatonin* |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
Interactions with Dietary Supplements
Melatonin
Taking mirtazapine results in enhanced secretion of melatonin at night;1 this may
explain part of the mechanism of the effects of mirtazapine. Controlled research is needed to
determine whether melatonin supplementation might enhance either the beneficial or the adverse
effects of mirtazapine.
Interactions with Foods and Other Compounds
Alcohol
Drinking alcoholic beverages while taking mirtazapine may enhance the effects of the drug,
including impairment of thinking, judgment, and performance of difficult tasks; therefore, it
should be avoided.2
References:
1. Palazidou E, Papadopoulos A, Sitsen A, et al. An alpha 2 adenoceptor antagonist, Org 3770, enhances nocturnal melatonin secretion in man. Psychopharmacology (Berl) 1989;97:115–7.
2. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 2109–11.
Copyright © 2002 Healthnotes, Inc. All rights reserved. www.healthnotes.com
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article.
Learn more about Healthnotes, the company.
Learn more about the authors of Safetychecker.
The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.
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