Metronidazole (vaginal) is an intravaginal antibiotic used to treat vaginal infections caused primarily by bacteria. Metronidazole is also available as oral and topical medications.
Safetychecker Summary
for Metronidazole Vaginal
(for details about the summarized interactions, read the full article)
|
Zinc |
|
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
Interactions with Dietary Supplements
Zinc
Four women whose vaginal infections caused by trichomonas (one-celled parasites) were not responding to oral and vaginal
metronidazole treatment alone, improved when a zinc sulfate douche was added.1
Controlled research is needed to determine if zinc enhances the effects of metronidazole in
vaginal infections caused by other organisms.
1. Houang ET, Ahmet Z, Lawrence AG. Successful treatment of four patients with recalcitrant vaginal trichomoniasis with a combination of zinc sulfate douche and metronidazole therapy. Sex Transm Dis 1997;24:116–9.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.