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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Timolol TIMOLOL Introduction Safetychecker summary Vitamin interactions Herb interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Combination drugs: Cosopt®, Moducren®, Prestim®, Timolide® Timolol is a beta-blocker drug used to lower blood pressure in people with hypertension, treat people after heart attacks, and prevent migraine headaches. Timolol is available alone and in a combination product used to lower blood pressure. Timolol is also available in eye drop and eye gel preparations used to lower high internal eye pressure due to glaucoma and other conditions. Safetychecker Summary for Timolol (for details about the summarized interactions, read the full article) May be Beneficial: Side effect reduction/prevention—Taking these supplements may help reduce the likelihood and/or severity of a potential side effect caused by the medication. Coenzyme Q10 Depletion or interference None known Supportive interaction None known Reduced drug absorption/bioavailability None known Adverse interaction None known Interactions with Dietary Supplements Coenzyme Q10 In a group of 16 glaucoma patients treated with a timolol eye preparation, six weeks of oral coenzyme Q10 (90 mg per day) was reported to reduce timolol-induced cardiovascular side effects without affecting intraocular pressure treatment.1 Potassium Some beta-adrenergic blockers (called “nonselective” beta blockers) decrease the uptake of potassium from the blood into the cells,2 leading to excess potassium in the blood, a potentially dangerous condition known as hyperkalemia.3 People taking beta-blockers should therefore avoid taking potassium supplements, or eating large quantities of fruit (e.g., bananas), unless directed to do so by their doctor. Interactions with Herbs Pleurisy root As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as beta-blockers.4 Interactions with Foods and Other Compounds Food Timolol may be taken with or without food.5 Alcohol Timolol may cause drowsiness, dizziness, lightheadedness, or blurred vision.6 Alcohol may intensify these effects and increase the risk of accidental injury. To prevent problems, people taking timolol should avoid alcohol. References: 1. Takahashi N, Iwasaka T, Sugiura T, et al. Effect of coenzyme Q10 on hemodynamic response to ocular timolol. J Cardiovasc Pharmacol 1989;14:462–8. 2. Rosa RM, Silva P, Young JB, et al. Adrenergic modulation of extrarenal potassium disposal. N Engl J Med 1980;302:431–4. 3. Lundborg P. The effect of adrenergic blockade on potassium concentrations in different conditions. Acta Med Scand Suppl 1983;672:121–6 [review]. 4. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213–4. 5. Mantyla R, Mannisto P, Nykanen S, et al. Pharmacokinetic interactions of timolol with vasodilating drugs, food and phenobarbitone in healthy human volunteers. Eur J Clin Pharmacol 1983;24:227–30. 6. Threlkeld DS, ed. Diuretics and Cardiovasculars, Beta-Adrenergic Blocking Agents. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1993, 158q. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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