REISHI

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Reishi

Parts used and where grown: Reishi mushrooms grow wild on decaying logs and tree stumps in the coastal provinces of China. The fruiting body of the mushroom is employed medicinally. Reishi grows in six different colors, but the red variety is most commonly used and commercially cultivated in North America, China, Taiwan, Japan, and Korea.¹

Reishi has been used in connection with the following conditions (refer to the individual health concern for complete information):

Rating	Health Concerns
	Altitude sickness Diabetes Hepatitis HIV support Hypertension Infection
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. An herb is primarily supported by traditional use, or the herb or supplement has little scientific support and/or minimal health benefit.

Historical or traditional use (may or may not be supported by scientific studies): Reishi has been used in Traditional Chinese Medicine for at least 2,000 years.² The Chinese name ling zhi translates as the “herb of spiritual potency” and was highly prized as an elixir of immortality.³ Its Traditional Chinese Medicine indications include treatment of general fatigue and weakness, asthma, insomnia, and cough.⁴

Active constituents: Reishi contains several major constituents, including sterols, coumarin, mannitol, polysaccharides, and triterpenoids called ganoderic acids. Ganoderic acids may lower blood pressure as well as decrease LDL (“bad”) cholesterol. These specific triterpenoids also help reduce blood platelets from sticking together—an important factor in lowering the risk for coronary artery disease. While human research has been reported that demonstrates some efficacy for the herb in treating altitude sickness and chronic hepatitis B, these uses still need to be confirmed in well-designed human trials.⁵ Animal studies and some very preliminary trials in humans suggest reishi may have some beneficial action in people with diabetes mellitus and cancer.⁶ Two controlled clinical trials have investigated the effects of reishi on high blood pressure in humans and both found it could lower blood pressure significantly compared to a placebo or controls.^{7 8} The people with hypertension in the second study had previously not responded to medications, though these were continued during the study.

How much is usually taken? Reishi can be taken either as 1.5–9 grams per day of the crude dried mushroom, 1–1.5 grams per day in powdered form, 1 ml per day of tincture, or as a tea.⁹

Are there any side effects or interactions? Side effects from reishi can include dizziness, dry mouth and throat, nosebleeds, and abdominal upset. These rare effects may develop with continuous use over three to six months.¹⁰ Pregnant or breast-feeding women should consult a physician before taking reishi.

Are there any drug interactions? Certain medications may interact with reishi. Refer to the drug interactions safety check for a list of those medications.

1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Foods, Drugs, and Cosmetics, 2d ed. New York: John Wiley & Sons, 1996, 255–60.

2. Jones K. Reishi: Ancient Herb for Modern Times. Issaquah, WA: Sylvan Press, 1990, 6.

3. Willard T. Reishi Mushroom: Herb of Spiritual Potency and Wonder. Issaquah, WA: Sylvan Press, 1990, 11.

4. Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 640–1.

5. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.

6. Jones K. Reishi mushroom: Ancient medicine in modern times. Alt Compl Ther 1998;4:256–66 [review].

7. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.

8. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.

9. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.

10. McGuffin M, Hobbs C, Upton R, Goldberg A (eds). American Herbal Products Association’s Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 55.

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