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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Zolpidem ZOLPIDEM Introduction Safetychecker summary Vitamin interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Zolpidem a is hypnotic drug used for short-term treatment of people with insomnia. Safetychecker Summary for Zolpidem (for details about the summarized interactions, read the full article) Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. 5-Hydroxytryptophan (5-HTP)* L-tryptophan* Depletion or interference None known Side effect reduction/prevention None known Supportive interaction None known Reduced drug absorption/bioavailability None known Interactions with Dietary Supplements 5-Hydroxytryptophan (5-HTP) and L-tryptophan Nine cases of zolpidem-induced hallucinations associated with serotonin reuptake inhibiting antidepressants have been reported, some lasting for several hours.1 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with zolpidem may increase zolpidem-induced hallucinations, though no interactions have yet been reported with zolpidem and 5-HTP or L-tryptophan. Interactions with Foods and Other Compounds Food Food may interfere with zolpidem absorption and slow the onset of sleep.2 Zolpidem should be taken one hour before or two hours after food to avoid this interaction. Alcohol Zolpidem causes drowsiness. Alcohol may compound this effect and increase the risk of accidental injury.3 To prevent problems, people taking zolpidem should avoid alcohol. References: 1. Elko CJ, Burgess JL, Robertson WO. Zolpidem-associated hallucinations and serotonin reuptake inhibition: a possible interaction. J Toxicol Clin Toxicol 1998;36:195–203. 2. Threlkeld DS, ed. Central Nervous System Drugs, Sedatives and Hypnotics, Nonbarbiturate, Imidazopyridines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1993, 269h–9m. 3. Threlkeld DS, ed. Central Nervous System Drugs, Sedatives And Hypnotics, Nonbarbiturate, Imidazopyridines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1993, 269h–9m. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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