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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Sumatriptan SUMATRIPTAN Introduction Safetychecker summary Vitamin interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Sumatriptan is a member of the selective serotonin receptor agonist family of drugs used to treat, but not prevent, migraine headaches. Sumatriptan is available in injection, nasal spray, and oral tablet forms. Safetychecker Summary for Sumatriptan (for details about the summarized interactions, read the full article) Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. 5-Hydroxytryptophan (5-HTP)* L-tryptophan* Depletion or interference None known Side effect reduction/prevention None known Supportive interaction None known Reduced drug absorption/bioavailability None known Interactions with Dietary Supplements 5-Hydroxytryptophan (5-HTP) and L-tryptophan Sumatriptan works by stimulating serotonin receptors in the brain. 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with sumatriptan could increase sumatriptan-induced side effects. However, no interactions have yet been reported with sumatriptan and 5-HTP or L-tryptophan. Interactions with Foods and Other Compounds Food Sumatriptan tablets may begin to work faster when taken with fluid on an empty stomach at the first sign of migraine.1 2 References: 1. Threlkeld DS, ed. Central Nervous System Drugs, Agents for Migraine, Serotonin 5-HT1 Receptor Agonists. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jun 1996, 256a. 2. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 253. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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