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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Lomotil®, Lonox® LOMOTIL®, LONOX® Introduction Safetychecker summary Herb interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale This is a combination drug containing two ingredients, diphenoxylate and atropine, that is used in the treatment of diarrhea. Diphenoxylate is in a class of drugs known as antidiarrheals. Safetychecker Summary for Lomotil, Lonox (for details about the summarized interactions, read the full article) Avoid: Reduced drug absorption/bioavailability—Avoid these supplements when taking this medication since the supplement may decrease the absorption and/or activity of the medication in the body. Tannin-containing herbs* such as green tea, black tea, uva ursi, black walnut, red raspberry, oak, and witch hazel Depletion or interference None known Side effect reduction/prevention None known Supportive interaction None known Adverse interaction None known Interactions with Herbs Tannin-containing herbs Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra), red raspberry (Rubus idaeus), oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of the drug when taken by mouth.1 Interactions with Foods and Other Compounds Alcohol Diphenoxylate may enhance the actions of alcohol,2 resulting in increased drowsiness, dizziness, imbalance, and poor response times. Therefore, people taking diphenoxylate should avoid alcohol, especially when staying alert is necessary. References: 1. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Institute, 1997, 100. 2. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 2923–4. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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