Current customer? Log In

	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Glyburide GLYBURIDE Introduction Safetychecker summary Herb interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Glyburide is a sulfonylurea drug used to lower blood sugar levels in people with type 2 (non-insulin-dependent) diabetes. Maintaining normal blood sugar levels helps reduce health problems associated with diabetes. People with diabetes should consult with their doctor before starting or stopping any form of treatment including drug therapy, herbal products, supplements, and others. Consumption of a high-fiber diet and/or supplementation with nutrients such as chromium, biotin, vitamin E, and others or herbs such as Gymnema sylvestre will often improve blood-sugar control in diabetics. In such cases, the amount of blood sugar-lowering drugs may need to be reduced in order to avoid a hypoglycemic reaction. Anyone taking medication for diabetes should consult the prescribing physician before making dietary changes or taking nutrients or herbs that are designed to lower blood-sugar levels. Safetychecker Summary for Glyburide (for details about the summarized interactions, read the full article) May be Beneficial: Supportive interaction—Taking these supplements may support or otherwise help your medication work better. Aloe vera* Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. Chromium* Ginkgo biloba Check: Other—Before taking any of these supplements or eating any of these foods with your medication, read this article in full for details. Biotin Gymnema sylvestre Vitamin E Depletion or interference None known Side effect reduction/prevention None known Reduced drug absorption/bioavailability None known Interactions with Herbs Aloe  (Aloe vera) One single-blind study in Thailand reported that combining 1 Tbsp (15 ml) of aloe juice twice daily with glyburide significantly improved blood sugar and lipid levels in people with diabetes, compared with placebo.1 Previously, glyburide by itself had not effectively controlled the diabetes in the people in this study. Ginkgo biloba* In a preliminary trial, administration of Ginkgo biloba extract (120 mg per day) for three months to patients with type 2 diabetes who were taking oral anti-diabetes medication resulted in a significant worsening of glucose tolerance. Ginkgo did not impair glucose tolerance in individuals whose diabetes was controlled by diet.2 Individuals taking oral anti-diabetes medication should consult a doctor before taking Ginkgo biloba. Interactions with Foods and Other Compounds Food Glyburide may be taken with food to avoid gastrointestinal (GI) upset.3 Effective treatment of type 2 diabetes with glyburide includes adherence to recommended dietary guidelines. Alcohol Alcohol consumption may interfere with blood-sugar control during glyburide therapy.4 Alcohol may interact with glyburide, causing facial flushing, headache, light-headedness, nausea, breathlessness, and other symptoms.5 People taking glyburide should avoid alcohol. References: 1. Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice. II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomed 1996;3:245–8. 2. Kudolo GB. The effect of 3-month ingestion of Ginkgo biloba extract (EGb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus. J Clin Pharmacol 2001;41:600–11. 3. Threlkeld DS, ed. Hormones, Antidiabetic Agents, Sulfonylureas. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jun 1992, 130m. 4. Threlkeld DS, ed. Hormones, Antidiabetic Agents, Sulfonylureas. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jun 1992, 130m. 5. Threlkeld DS, ed. Hormones, Antidiabetic Agents, Sulfonylureas. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Jun 1992, 130m. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

Accept Credit Cards Online

New! 24x7 Ordering by Phone. Call 1-800-439-5506

Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Information about each product is taken from the labels of the products or from the manufacturer's advertising material. MotherNature.com is not responsible for any statements or claims that various manufacturers make about their products. We cannot be held responsible for typographical errors or product formulation changes. You should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.All discounts are taken from suggested retail prices.

Please see our Terms of Use
Copyright © 1995-2009 Mother Nature, Inc. All rights reserved.