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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Bupropion BUPROPION Introduction Safetychecker summary Herb interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Bupropion is used to treat people with depression and to aid in smoking cessation treatment. Safetychecker Summary for Bupropion (for details about the summarized interactions, read the full article) May be Beneficial: Supportive interaction—Taking these supplements may support or otherwise help your medication work better. Yohimbine* Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. Alcohol Depletion or interference None known Side effect reduction/prevention None known Reduced drug absorption/bioavailability None known Interactions with Herbs Yohimbine A 50-year-old woman who was unresponsive to traditional antidepressant therapy was reported to have a marked and persistent improvement in mood when yohimbine was added to her bupropion therapy.1 Further research is necessary to determine the significance of this finding. Interactions with Foods and Other Compounds Alcohol Unlike most other antidepressant drugs, there is no evidence that alcohol causes significant changes in blood levels of bupropion.2 However, people taking bupropion who are also attempting to discontinue chronic alcohol consumption have been reported to sometimes experience convulsions.3 References: 1. Pollack MH, Hamerness P. Adjunctive yohimbine for treatment in refractory depression. Biol Psychiatry 1993;33:220–1. 2. Posner J, Bye A, Jeal S, et al. Alcohol and bupropion pharmacokinetics in healthy male volunteers. Eur J Clin Pharmacol 1984;26:627–30. 3. Storrow AB. Bupropion overdose and seizure. Am J Emerg Med 1994;12:183–4. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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