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MINERAL OIL

Mineral oil is a laxative used to soften stools in people with constipation. Mineral oil is also used as a vehicle to carry other ingredients in some topical skin products.

Safetychecker Summary for Mineral Oil
(for details about the summarized interactions, read the full article)

Beneficial May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them.

Beta-carotene

Calcium*

Potassium*

Vitamin A*

Vitamin D*

Vitamin E*

Vitamin K*

Phosphorus*

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

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Interactions with Dietary Supplements

Vitamins and minerals
Mineral oil has interfered with the absorption of many nutrients, including beta-carotene, calcium, phosphorus, potassium, and vitamins A, D, K, and E in some,1 but not all,2 research. Taking mineral oil on an empty stomach may reduce this interference. It makes sense to take a daily multivitamin-mineral supplement two hours before or after mineral oil. It is important to read labels, because many multivitamins do not contain vitamin K or contain inadequate (less than 100 mcg per day) amounts.

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References: Top

1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 176.

2. Clark JH, Russell GJ, Fitzgerald JF, Nagamori KE. Serum beta-carotene, retinol, and alpha-tocopherol levels during mineral oil therapy for constipation. Am J Dis Child 1987;141:1210–2.

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