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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Hydralazine HYDRALAZINE Introduction Safetychecker summary Vitamin interactions Food interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Combination drug: Apresazide® Hydralazine is a drug used to lower blood pressure in people with hypertension. Hydralazine relaxes the muscles that control the diameter of blood vessels. This relaxation allows the blood vessels to dilate (open wider), lowering blood pressure. Safetychecker Summary for Hydralazine (for details about the summarized interactions, read the full article) May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them. Vitamin B6 Side effect reduction/prevention None known Supportive interaction None known Reduced drug absorption/bioavailability None known Adverse interaction None known Interactions with Dietary Supplements Vitamin B6 Vitamin B6 can bind to hydralazine to form a complex that is excreted in the urine, increasing vitamin B6 loss.1 This may lead to vitamin B6 deficiency.2 People taking hydralazine should consult with their doctor to discuss the possibility of vitamin B6 supplementation. Interactions with Foods and Other Compounds Food Taking hydralazine with food improves the absorption of the drug.3 People with questions should ask their prescribing doctor or pharmacist. Alcohol Alcohol causes blood vessels to dilate, lowering blood pressure. This action may add to the blood pressure-lowering effect of hydralazine and increase the risk of dizziness, fainting, or accidental falls. People taking hydralazine should avoid alcohol and should read all product labels carefully for alcohol content. References: 1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 131–2. 2. Raskin NH, Rishman RA. Pyridoxine-deficiency neuropathy due to hydralazine. N Engl J Med 1965;273:1182–5. 3. Threlkeld DS, ed. Diuretics and Cardiovasculars, Antihypertensives, Vasodilators, Hydralazine. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Dec 1993, 163r–4b. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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