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	Search Quick Order Form» Departments Vitamins Minerals Supplements Herbs Home & Grocery Diet & Fitness Body & Bath More Ways to Shop Brands A-Z Natural Remedies Children & Infants Women's Health Men's Health Seniors Free Catalog MotherNature.com's Catalog Is Here! Click Here to Get Your Free Copy Today. Newsletter Sign Up Weekly health news, sale announcements and coupons!		Library Home > Safetychecker by Drug Name > Colchicine COLCHICINE Introduction Safetychecker summary Vitamin interactions References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale Colchicine reduces the inflammatory (swelling) response and pain in people with gout (high uric acid blood levels leading to painful accumulation of uric acid crystals in and around joints). Safetychecker Summary for Colchicine (for details about the summarized interactions, read the full article) May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them. Beta-carotene* Potassium* Vitamin B12* Check: Other—Before taking any of these supplements or eating any of these foods with your medication, read this article in full for details. Sodium Side effect reduction/prevention None known Supportive interaction None known Reduced drug absorption/bioavailability None known Adverse interaction None known Interactions with Dietary Supplements Vitamin B12 Colchicine may interfere with vitamin B12 in the body. Research is inconsistent. Both colchicine and vitamin B12 deficiency are reported to cause neuropathies (disorders of the nervous system), but it remains unclear whether neuropathies caused by colchicine could be due to vitamin B12 depletion.1 2 Nutrient malabsorption Colchicine has been associated with impaired absorption of beta-carotene, fat, lactose (milk sugar), potassium, and sodium.3 References: 1. Palopoli JJ, Waxman J. Colchicine neuropathy or vitamin B12 deficiency neuropathy? N Engl J Med 1987;317:1290 [letter]. 2. Kuncl RW et al. Colchicine neuropathy or vitamin B12 deficiency neuropathy? N Engl J Med 1987;317:1290–1 [letter]. 3. Werbach MR. Foundations of Nutritional Medicine. Tarzana, CA: Third Line Press, 1997, 223–4 [review]. Copyright © 2002 Healthnotes, Inc.  All rights reserved. www.healthnotes.com Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. Learn more about Healthnotes, the company. Learn more about the authors of Safetychecker. The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.

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